5 Signs That Your Child is Suffering from Hunter’s Syndrome

Child with Hunter’s Syndrome

Hunter Syndrome, or mucopolysaccharidosis II (MPS II), is a rare genetically inherited ailment that mainly affects young boys. The disorder occurs when the body lacks iduronate 2-sulfatase, an enzyme that normally breaks specific complex molecules inside the body. This leads to the build-up of the molecules to a harmful level, impairing the normal body functioning.

As the complex molecules continue to pile up in the body tissues, they start to initiate progressive damages in the body. They can alter the appearance of your child and cause mental illness, organ malfunction, and physical disabilities. Therefore, when looking for Bali medical check-up centers for regular health checks, it is best to look for the following signs and symptoms to know the health status of your child:

1. Abnormal physical appearance

The most common sign is deformed or abnormal physical appearance. This includes unusual facial features such as a broad nose, bushy eyebrows, large heads, thick lips, and massive round cheeks. According to WebMD.com, some patients will also portray symptoms such as inflated head, short and broad hands, stiff fingers, thick and tight skin, and overall slowed growth.

2. Joint problems

Joint problems is another common symptom among children suffering from Hunter’s syndrome. According to The Cleveland Clinic, the disease results in joint discomfort along with other body parts such as the spine, knees, feet, hands, and hips.

Usually, you will see your kid moving around with limited motion due to joint stiffness. They may experience difficulties in picking objects since progressive involvement of body parts such as the hips, spine, and fingers come with joint pain.

3. Respiratory problems

Respiratory problems normally take place when the complex molecules accumulate in and around respiratory organs. As a result, patients fall vulnerable to upper airway diseases or cardiovascular failure.

sad child

4. Digestion problems

Hunter’s syndrome results in a reduced rate of detoxification in the digestive system. This means that a good amount of ingested toxins will accumulate in the stomach and intestine, impairing the functionality of primary enzymes such as pepsin. Additionally, the toxins affect crucial digestion organs such as the pancreas. Digestive problems related to the condition include enlarged liver or spleen and bowel problems such as diarrhea, constipation, and perianal infections.

5. Cardiovascular problems

Hunter’s syndrome does not exempt the cardiovascular system since it touches on vital body organs that are directly involved in the efficient functions of the body. According to Science Direct, the disorder causes the accumulation of molecules along the arteries and veins. The end result is cardiac arrest, heart failure, high blood pressure, and even death.


According to a study published in the U.S. National Library of Medicine, kids born with Hunter’s syndrome grow normal until around the age of two. That is when the symptoms start to develop intensely. By going for a timely diagnosis that entails a separate examination of molecular, chemical, and clinical parameters, you can immensely improve your kids’ health status.

Remember, there is no cure for Hunter’s syndrome. If your kid is a victim, then how you work to maintain the situation will significantly determine their health.


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